Litigating the validity of claims in an inter partes review (IPR) at the Patent Trial and Appeal Board (PTAB) is vastly different from litigating validity in district court. PTAB judges are scientists and engineers, and they are also patent attorneys. They have significant technical training, and most have advanced technical degrees. You can assume they know substantive patent law cold. PTAB judges represent a very different audience from a lay judge or a jury in district court.
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